ProHance^® (gadoteridol) is a contrast medium for magnetic resonance imaging (MRI) in the form of a sterile, apyrogenic solution for intravenous injection. In MRI, ProHance^® provides contrast enhancement of the brain, spine and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to cause a disruption of the normal blood-brain barrier. ProHance^® can also be used for whole-body MRI, including the head, neck, liver, breast, musculoskeletal system, and soft tissue pathologies.